The Cod Army have never even played against top flight opposition before, let alone made it past this round of the competition.
The hosts did need a replay to make it past Hereford in the last round after being held to a 1-1 draw in the original tie, and you can get odds of 3/1 (4.00) on them playing out another stalemate here.
Wes Morgan, Danny Simpson and Robert Huth remain injured for the visitors, but Jamie Vardy is hoping to return to face his former club after missing out on Monday’s win over Huddersfield.
For the Cod Army, striker Conor McAleny continues to be eased back into the side by Uwe Rosler, while Bobby Grant is also eyeing a return after a long lay-off.
Although McAleny’s absence has not been too keenly felt thanks to the prolific form of Devante Cole in attack, Fleetwood have had more problems at the other end of the pitch this season.
Having scored more goals than second-placed Shrewsbury in League One, they have also conceded more than all but four other teams themselves.
While they may therefore fancy their chances of having some joy against an opposition defence that has kept just one clean sheet in eight, the lower league outfit will surely struggle to keep things tight at the back.